20210214

Contents
  1. 1. Working directories
    1. 1.1. Kaiju: Fast and sensitive taxonomic classification for metagenomics
    2. 1.2. Windows 10 VB download
  2. 2. NSFC Application
  3. 3. Accessable directory in a mobile phone with command-line
  4. 4. Vaccine in US
    1. 4.1. App, v-safe
    2. 4.2. Immuno-suppresive
    3. 4.3. Pfizer
    4. 4.4. Moderna
    5. 4.5. Sputnik V

Working directories

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i=/media/ht/ht_5T/Bioinformatics/Bioinfo-Softs/NCBI/Datasets
pcmanfm -n ${i}; cd ${i} # NCBI Datasets command-line # See NCBI_Learning.html
#
# Remote BWA with Vision
# E-MTAB-173, Essential
#
i=/media/ht/ht_5T/Work/Projects/Phage
pcmanfm -n ${i}; cd ${i} # Phage RnD Powerpoint updated
#
i=/media/ht/ht_5T/Work/Projects/Phage/Phage_RnD_Background_20210214.pptx
setsid wpp ${i} # Phage RnD Powerpoint updated
#
i='/media/ht/ht_5T/Work/Projects/Phage/Phage_RnD_Background.pptx'; setsid wps ${i}
#
i=/media/ht/ht_5T_9/YouTubes/History/Wuhan/Vaccine/CDC_美国接种4百万Moderna新冠疫苗后的严重过敏反应数据分析.mp4
setsid vlc ${i}
#
i=/media/ht/ht_5T_9/YouTubes/English/German/德文字母及其發音介紹-母音及Umlaut發音練習-Das_deutsche_Alphabet-全程中文說明.mp4
setsid vlc ${i}

Kaiju: Fast and sensitive taxonomic classification for metagenomics

Publication downloaded from URL as below

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i=/media/ht/ht_5T/Bioinformatics/Bioinfo-Softs/NGS_Softs/Kaiju
pcmanfm -n ${i}; cd ${i} # Kaiju

Windows 10 VB download

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i=https://az792536.vo.msecnd.net/vms/VMBuild_20190311/VirtualBox/MSEdge/MSEdge.Win10.VirtualBox.zip
axel -q -n 10 ${i}
Windows 10 Download Sites

NSFC Application

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#
i='/media/ht/ht_5T/Work/Funding/2021_国家自然科学基金'; pcmanfm -n ${i}; cd ${i} # NSFC
  • 信息科学部案例, P6
  • Code, 医学, H2103, H1904. 肝炎病毒与感染
  • Code, 生命科学, C06, 生物信息理论方法

Accessable directory in a mobile phone with command-line

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i=/run/user/1000/gvfs/ftp:host=192.168.1.8,port=2121,user=ht/Download/
pcmanfm -n ${i}; cd ${i}

Vaccine in US

Vaccine efficacy

App, v-safe

v-safe

Priority and coverage of vaccine

  1. 5%
  2. 30%
  3. 40%

Immuno-suppresive

tacrolimus, cyclosporine, mycophenolate, azathioprine, sirolimus

  • EpiPen 2-Pak, 过敏

Other names: Epinephrine, adrenaline, adrenalin

Adrenaline, also known as epinephrine, is a hormone and medication which is involved in regulating visceral functions (e.g., respiration).. Adrenaline is normally produced both by the adrenal glands and by a small number of neurons in the medulla oblongata.

Generic Name: epinephrine injection (EP i NEF rin)
Brand Name: Adrenalin, Auvi-Q, Epinephrinesnap-EMS, Epinephrinesnap-V, EpiPen 2-Pak, EpiPen JR 2-Pak, EPIsnap, Symjepi

EpiPen 2-Pak is used to treat severe allergic reactions (anaphylaxis) to insect stings or bites, foods, drugs, and other allergens.

Epinephrine auto-injectors may be kept on hand for self-injection by a person with a history of severe allergic reaction.

Epinephrine is also used to treat exercise-induced anaphylaxis, or to treat low blood pressure that is caused by septic shock.

EpiPen 2-Pak may also be used for purposes not listed in this medication guide.

Pfizer

  • 44 K
  • Placebo, 162, 9 heavy
  • Vaccine, 8, 1 heavy
  • 5 shots / vial, 0.3 ml / shot. Dilution needed

Moderna

  • 30 K
  • Placebo, 185, 30 heavy
  • Vaccine, 11, 0 heavy
  • 10 shots / vial, 0.5 ml / shot

The trial began on July 27, 2020, and enrolled 30,420 adult volunteers at clinical research sites across the United States. Volunteers were randomly assigned 1:1 to receive either two 100 microgram (mcg) doses of the investigational vaccine or two shots of saline placebo 28 days apart. The average age of volunteers is 51 years. Approximately 47% are female, 25% are 65 years or older and 17% are under the age of 65 with medical conditions placing them at higher risk for severe COVID-19. Approximately 79% of participants are white, 10% are Black or African American, 5% are Asian, 0.8% are American Indian or Alaska Native, 0.2% are Native Hawaiian or Other Pacific Islander, 2% are multiracial, and 21% (of any race) are Hispanic or Latino.

From the start of the trial through Nov. 25, 2020, investigators recorded 196 cases of symptomatic COVID-19 occurring among participants at least 14 days after they received their second shot. One hundred and eighty-five cases (30 of which were classified as severe COVID-19) occurred in the placebo group and 11 cases (0 of which were classified as severe COVID-19) occurred in the group receiving mRNA-1273. The incidence of symptomatic COVID-19 was 94.1% lower in those participants who received mRNA-1273 as compared to those receiving placebo.

Investigators observed 236 cases of symptomatic COVID-19 among participants at least 14 days after they received their first shot, with 225 cases in the placebo group and 11 cases in the group receiving mRNA-1273. The vaccine efficacy was 95.2% for this secondary analysis.

  • 0.2-0.3 % death rate (Mortality rate) of flu
  • 1.8 % death rate of COVID-19

Sputnik V

Sputnik V

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